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Article

Deep immune-phenotyping of HLA-homozygous iPS-cardiomyocytes by spectral flow cytometry.

Frontiers in immunology - 1 Jan 2026

Maeding Nicole, Suresh Kundully Deepika, Steinhuber Anna, Kriedemann Nils, Hernandez-Bautista Carlos A, Martins Soraia, Hochmann Sarah, Wolf Martin, Mayr Wolfgang, Jungbauer Christof, Diecke Sebastian, Tonn Torsten, Greber Boris, Zweigerdt Robert, Strunk Dirk

Abstract excerpt

Introduction: Immunogenicity of allogeneic human induced pluripotent stem cell (hiPSC)-derived transplants limits their applicability in regenerative medicine. Selecting human leukocyte antigen (HLA)-homozygous hiPSC lines could be a mitigation strategy and haplo-matching would profoundly expand the number of potential recipients. Here we show deep immune-phenotyping of hiPSC-derived cardiomyocytes (iPS-CM)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41716415
DOI: 10.3389/fimmu.2026.1736994
PMCID: PMC12913090

Genes

CD47

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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