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Article

A call to adopt a "fit for purpose" approach to antibody validation for flow cytometry analyses of stem cell models and beyond.

American journal of physiology. Heart and circulatory physiology - 1 Nov 2019

Waas Matthew, Gundry Rebekah L

Abstract excerpt

Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) can be exploited as models for a wide range of research applications and numerous protocols for generating hPSC-CMs have been described. However, it is currently not possible to direct differentiation to a single, homogeneous end point, and the resulting heterogeneity may be variable among laboratories, cell lines, and protocols. Consequently, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 31559827
DOI: 10.1152/ajpheart.00347.2019
PMCID: PMC6879911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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