Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular and phenotypic analyses of human embryonic stem cell-derived cardiomyocytes: opportunities and challenges for clinical translation.

Thrombosis and haemostasis - 1 Oct 2005

Goh Gareth, Self Tim, Barbadillo Muñoz Maria D, Hall Ian P, Young Lorraine, Denning Chris

Abstract excerpt

Differentiation of human embryonic stem cells (hESCs) into cardiomyocytes in culture may offer unique opportunities for modeling genetic disorders, screening potentially cardiotoxic pharmaceutical agents or replacing cells of the diseased heart. However, before clinical utility can be realized, numerous hurdles must be overcome. Comprehensive molecular and phenotypic characterization is required but has so far...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Differentiation
Share to Heart Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Myocytes, Cardiac

Share to Phenotype

Share to Stem Cell Transplantation

Share to Stem Cells

Share to Transcription, Genetic

Source

Identifiers

PMID: 16270624
DOI: 10.1160/TH05-04-0268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular and phenotypic analyses of human embryonic stem cell-derived cardiomyocytes: opportunities and challenges for clinical translation.PMID 16270624Read ↗

Embryonic stem cells and cardiomyocyte differentiation: phenotypic and molecular analyses.Semantic proximity Read ↗

Human induced pluripotent stem cell-derived cardiomyocytes: insights into molecular, cellular, and functional phenotypes.Semantic proximity Read ↗

Induced Pluripotent Stem Cells Technology and Cardiomyocyte Generation: Progress, Uncertainties and Challenges in the Biological Features and Clinical ApplicationsSemantic proximity Read ↗

Human embryonic stem cells and cardiac repair.Semantic proximity Read ↗

Human pluripotent stem cell-derived cardiomyocytes for heart regeneration, drug discovery and disease modeling: from the genetic, epigenetic, and tissue modeling perspectivesSemantic proximity Read ↗

Differentiation of pluripotent embryonic stem cells into cardiomyocytes.Semantic proximity Read ↗

Cardiomyocytes from human pluripotent stem cells: From laboratory curiosity to industrial biomedical platform.Semantic proximity Read ↗

Characterization and Enrichment of Cardiomyocytes Derived From Human Embryonic Stem CellsSemantic proximity Read ↗

Cardiac Regeneration using Human Embryonic Stem Cells: Producing Cells for Future TherapySemantic proximity Read ↗

Efficient Generation and Cryopreservation of Cardiomyocytes Derived from Human Embryonic Stem CellsSemantic proximity Read ↗

Induced pluripotent stem cells in the inherited cardiomyopathies: From disease mechanisms to novel therapies.Semantic proximity Read ↗

Human Pluripotent Stem Cell-Derived Cardiomyocytes as Research and Therapeutic ToolsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.