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A Homozygous Dab1-/- Is a Potential Novel Cause of Autosomal Recessive Congenital Anomalies of the Mice Kidney and Urinary Tract.

Biomolecules - 20 Apr 2021

Racetin Anita, Filipović Natalija, Lozić Mirela, Ogata Masaki, Gudelj Ensor Larissa, Kelam Nela, Kovačević Petra, Watanabe Koichiro, Katsuyama Yu, Saraga-Babić Mirna, Glavina Durdov Merica, Vukojević Katarina

Abstract excerpt

This study aimed to explore morphology changes in the kidneys of Dab1-/- (yotari) mice, as well as expression patterns of reelin, NOTCH2, LC3B, and cleaved caspase3 (CASP3) proteins, as potential determinants of normal kidney formation and function. We assumed that Dab1 functional inactivation may cause disorder in a wide spectrum of congenital anomalies of the kidney and urinary tract (CAKUT). Animals were...

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Identifiers

PMID: 33924028
DOI: 10.3390/biom11040609
PMCID: PMC8073787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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