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Article

Congenital anomalies of the kidney and urinary tract genetics in mice and men.

Nephrology (Carlton, Vic.) - 1 May 2015

Caruana Georgina, Bertram John F

Abstract excerpt

The most common cause of paediatric end-stage kidney disease results from congenital anomalies of the kidney and urinary tract (CAKUT). Genetic manipulation in mice has provided insight into the developmental events that give rise to the broad spectrum of malformations associated with CAKUT. Despite the increase in the number of identified CAKUT-causing genes, the underlying genetic cause for the majority of...

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PMID: 25605230
DOI: 10.1111/nep.12402

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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