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Article

Early B-cell factor 1 is an essential transcription factor for postnatal glomerular maturation.

Kidney international - 1 May 2014

Fretz Jackie A, Nelson Tracy, Velazquez Heino, Xi Yougen, Moeckel Gilbert W, Horowitz Mark C

Abstract excerpt

The coordination of multiple cytokines and transcription factors with their downstream signaling pathways has been shown to be integral to nephron maturation. Here we present a completely novel role for the helix-loop-helix transcription factor Early B-cell factor 1 (Ebf1), originally identified for B-cell maturation, for the proper maturation of glomerular cells from mesenchymal progenitors. The expression of...

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Identifiers

PMID: 24172684
DOI: 10.1038/ki.2013.433
PMCID: PMC4006322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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