Article
The Cytokine Network in Colorectal Cancer: Implications for New Treatment Strategies.
Cells - 29 Dec 2022
Braumüller Heidi, Mauerer Bernhard, Andris Johanna, Berlin Christopher, Wieder Thomas, Kesselring Rebecca
Abstract excerpt
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is not only a genetic disease with several mutations in specific oncogenes and/or tumor suppressor genes such as APC, KRAS, PIC3CA, BRAF, SMAD4 or TP53 but also a multifactorial disease including environmental factors. Cancer cells communicate with their environment mostly via soluble factors...
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