Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LNRRIL 6, a novel long noncoding RNA , protects colorectal cancer cells by activating the IL ‐6– STAT 3 pathway

27 Jun 2019

Abstract excerpt

Long noncoding RNAs (lncRNAs) are emerging as critical regulators of cancer. There is a comparable number of lncRNAs to protein-coding genes, but the expression patterns, functions, and molecular mechanisms of most lncRNAs in colorectal cancer (CRC) remain unclear. In this study, we report the identification of a novel lncRNA, named long noncoding RNA regulating IL-6 transcription (LNRRIL6), which is upregulated...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Mycobacterium research and diagnosis
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31246342
DOI: 10.1002/1878-0261.12538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LNRRIL 6, a novel long noncoding RNA , protects colorectal cancer cells by activating the IL ‐6– STAT 3 pathwayPMID 31246342Read ↗

The IL-6/JAK/STAT3 pathway: Potential therapeutic strategies in treating colorectal cancerSemantic proximity Read ↗

A Potential Role of IL-6/IL-6R in the Development and Management of Colon CancerSemantic proximity Read ↗

Interleukin-6 as a Pan-Cancer Prognostic Inflammatory Biomarker: A Population-Based Study and Comprehensive Bioinformatics AnalysisSemantic proximity Read ↗

Identification of an m6A-related lncRNA prognostic signature in colorectal cancer.Semantic proximity Read ↗

Discovery of a novel six‐long non‐coding RNA signature predicting survival of colorectal cancer patientsSemantic proximity Read ↗

The Prognostic Role of the IL-6 and RBP4 in Colorectal CancerSemantic proximity Read ↗

Long non-coding RNA RP11-468E2.5 curtails colorectal cancer cell proliferation and stimulates apoptosis via the JAK/STAT signaling pathway by targeting STAT5 and STAT6Semantic proximity Read ↗

Long non-coding RNAs and JAK/STAT signaling pathway regulation in colorectal cancer developmentSemantic proximity Read ↗

More than a sidekick: the IL-6 family cytokine IL-11 links inflammation to cancerSemantic proximity Read ↗

Blockade of IL-6 inhibits tumor immune evasion and improves anti–PD-1 immunotherapySemantic proximity Read ↗

Aberrantly expressed Fra-1 by IL-6/STAT3 transactivation promotes colorectal cancer aggressiveness through epithelial–mesenchymal transitionSemantic proximity Read ↗

ART1 knockdown decreases IL-6-induced proliferation activity in colorectal cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.