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Article

Lysine 53 Acetylation of Cytochrome c in Prostate Cancer: Warburg Metabolism and Evasion of Apoptosis.

Cells - 3 Apr 2021

Bazylianska Viktoriia, Kalpage Hasini A, Wan Junmei, Vaishnav Asmita, Mahapatra Gargi, Turner Alice A, Chowdhury Dipanwita Dutta, Kim Katherine, Morse Paul T, Lee Icksoo, Brunzelle Joseph S, Polin Lisa, Subedi Prabal, Heath Elisabeth I, Podgorski Izabela, Marcus Katrin, Edwards Brian F P, Hüttemann Maik

Abstract excerpt

Prostate cancer is the second leading cause of cancer-related death in men. Two classic cancer hallmarks are a metabolic switch from oxidative phosphorylation (OxPhos) to glycolysis, known as the Warburg effect, and resistance to cell death. Cytochrome c (Cytc) is at the intersection of both pathways, as it is essential for electron transport in mitochondrial respiration and a trigger of intrinsic apoptosis when...

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Identifiers

PMID: 33916826
DOI: 10.3390/cells10040802
PMCID: PMC8066186

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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