Article

Reduced Catalase Enzymatic Activity in Prostate Cancer Independent of L299F and A333T Variants

2026-01-22

Abstract excerpt

<h4>Background: </h4> /Objectives: Catalase (CAT) plays a pivotal role in cellular redox homeostasis by catalyzing the decomposition of hydrogen peroxide, thereby mitigating oxidative damage. Impaired CAT function has been linked to chronic inflammation, deregulated cell proliferation, and oncogenesis. While numerous CAT variants have been reported, their functional relevance in prostate cancer (PCa) remains uncle...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 456290e7-0424-5e73-87e8-9e539b390cc5
DOI: 10.20944/preprints202601.1644.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Reduced Catalase Enzymatic Activity in Prostate Cancer Independent of L299F and A333T VariantsDOI 10.20944/preprints202601.1644.v1Read

The Role of Catalase C262T Gene Polymorphism in the Susceptibility and Survival of Cancers.Semantic proximity Read

Catalase C-262T polymorphism and risk of prostate cancer: evidence from meta-analysis.Semantic proximity Read

The catalase C-262T gene polymorphism and cancer risk: a systematic review and meta-analysis.Semantic proximity Read

The association between polymorphisms in prooxidant or antioxidant enzymes (myeloperoxidase, SOD2, and CAT) and genes and prostate cancer risk in the Chinese population of Han nationality.Semantic proximity Read

Two common functional catalase gene polymorphisms (rs1001179 and rs794316) and cancer susceptibility: evidence from 14,942 cancer cases and 43,285 controls.Semantic proximity Read

Human catalase, its polymorphisms, regulation and changes of its activity in different diseases.Semantic proximity Read

Oxidative stress-related genetic variants, pro- and antioxidant intake and status, and advanced prostate cancer risk.Semantic proximity Read

Clinical relevance of protein-truncating variants of germline DNA repair genes in prostate cancer.Semantic proximity Read

Genetic variants of antioxidant and xenobiotic metabolizing enzymes and their association with prostate cancer: A meta-analysis and functional in silico analysis.Semantic proximity Read

Genetic Polymorphism of CAT C-262 T and Susceptibility to Breast Cancer, a Case-Control Study and Meta-Analysis of the Literatures.Semantic proximity Read

Polymorphisms of eNOS, catalase, and myeloperoxidase genes in prostate cancer in Turkish men: preliminary results.Semantic proximity Read

Polymorphisms in oxidative stress pathway genes and prostate cancer risk.Semantic proximity Read