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Article

Structural and functional insights into lysine acetylation of cytochrome c using mimetic point mutants.

FEBS open bio - 1 Dec 2021

Márquez Inmaculada, Pérez-Mejías Gonzalo, Guerra-Castellano Alejandra, Olloqui-Sariego José Luis, Andreu Rafael, Calvente Juan José, De la Rosa Miguel A, Díaz-Moreno Irene

Abstract excerpt

Post-translational modifications frequently modulate protein functions. Lysine acetylation in particular plays a key role in interactions between respiratory cytochrome c and its metabolic partners. To date, in vivo acetylation of lysines at positions 8 and 53 has specifically been identified in mammalian cytochrome c, but little is known about the structural basis of acetylation-induced functional changes. Here,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34455704
DOI: 10.1002/2211-5463.13284
PMCID: PMC8634867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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