Article
Distinct Response to Platinum-Based Chemotherapy among Patients with Metastatic Castration-Resistant Prostate Cancer Harboring Alterations in Genes Involved in Homologous Recombination.
The Journal of urology - 1 Sept 2021
Fan Liancheng, Fei Xiaochen, Zhu Yinjie, Chi Chenfei, Pan Jiahua, Sha Jianjun, Xin Zhixiang, Gong Yiming, Du Xinxing, Wang Yanqing, Dong Baijun, Xue Wei
Abstract excerpt
PURPOSE: We aimed to explore the association between genomic status and clinical outcome of platinum-based chemotherapy among patients with metastatic castration-resistant prostate cancer (mCRPC). MATERIALS AND METHODS: We conducted a retrospective study of 55 patients with mCRPC who received platinum-based chemotherapy after the progression to docetaxel chemotherapy and underwent genomic profiling of 14...
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