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Prognostic value of genomic mutations in metastatic prostate cancer

17 Feb 2023

Abstract excerpt

Metastatic prostate cancer (mPC) has a poor prognosis, and new treatment strategies are currently being offered for patients in clinical practice, but mPC is still incurable. A considerable proportion of patients with mPC harbor homologous recombination repair (HRR) mutations, which may be more sensitive to poly (ADP-ribose) polymerase inhibitors (PARPis). We retrospectively included genomic and clinical data...

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Cancer Genomics and Diagnostics
PARP inhibition in cancer therapy
Prostate Cancer Treatment and Research

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36895385
DOI: 10.1016/j.heliyon.2023.e13827

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