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Genomic Landscape of Osteosarcoma of Bone in an Older-Aged Patient Population and Analysis of Possible Etiologies Based on Molecular Signature.

Genetic testing and molecular biomarkers - 1 Sept 2024

Kaseb Hatem, Tan Chichun, Townsend Jeffrey P, Costa Jose, Laskin William B

Abstract excerpt

Background: Osteosarcoma (OS), the most common primary malignant bone tumor, occurs mostly in the pediatric and adolescent (P/A) population where it has been subject to intense study whereas OS arising in the older-aged adult population has undergone less scrutiny. Materials and Methods: In this study, we assess the molecular aberrations detected in eight older adult patients (>59 years of age) with OS of bone by...

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PMID: 39052504
DOI: 10.1089/gtmb.2024.0080

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