Role of FTO gene polymorphisms in Wilms tumor predisposition: A five-center case-control study.

doi:10.1002/jgm.3348

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Article

Role of FTO gene polymorphisms in Wilms tumor predisposition: A five-center case-control study.

The journal of gene medicine - 1 Aug 2021

Hua Rui-Xi, Fu Wen, Lin Ao, Zhou Haixia, Cheng Jiwen, Zhang Jiao, Li Suhong, Liu Guochang, Xia Huimin, Zhuo Zhenjian, He Jing

Abstract excerpt

BACKGROUND: Wilms tumor is the most frequently occurring renal malignancy in pediatrics. The FTO gene exhibits a featured genetic contribution to cancer development. Nonetheless, its single nucleotide polymorphism (SNP) contribution to Wilms tumor remains unknown. METHODS: In the present study, 402 Wilms tumor patients and 1198 healthy controls were successfully genotyped for FTO gene SNPs (rs1477196 G>A,...

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PMID: 33894035
DOI: 10.1002/jgm.3348

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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