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Article

Homocysteine-reducing B vitamins and ischemic heart disease: a separate-sample Mendelian randomization analysis.

European journal of clinical nutrition - 1 Feb 2017

Zhao J V, Schooling C M

Abstract excerpt

BACKGROUND/OBJECTIVES: Observationally, homocysteine is positively associated with ischemic heart disease (IHD) and unhealthy lipids; folate and vitamin B12, which reduce homocysteine, are associated with lower IHD risk and healthy lipids. Randomized controlled trials have shown no benefits of folate and vitamin B12 for IHD. To clarify the role of these potential targets of intervention in IHD we assessed how...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27901035
DOI: 10.1038/ejcn.2016.246

Genes

CAD

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