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Article

Five-Year Change in Body Mass Index Predicts Conversion to Mild Cognitive Impairment or Dementia Only in APOE ɛ4 Allele Carriers.

Journal of Alzheimer's disease : JAD - 1 Jan 2021

Kadey Kylie R, Woodard John L, Moll Allison C, Nielson Kristy A, Smith J Carson, Durgerian Sally, Rao Stephen M

Abstract excerpt

BACKGROUND: Body mass index (BMI) has been identified as an important modifiable lifestyle risk factor for dementia, but less is known about how BMI might interact with Apolipoprotein E ɛ4 (APOE ɛ4) carrier status to predict conversion to mild cognitive impairment (MCI) and dementia. OBJECTIVE: The aim of this study was to investigate the interaction between APOE ɛ4 status and baseline (bBMI) and five-year BMI...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33749649
DOI: 10.3233/JAD-201360
PMCID: PMC10735532

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