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Article

Age-dependent effects of body mass index across the adult life span on the risk of dementia: a cohort study with a genetic approach.

BMC medicine - 9 Jun 2020

Karlsson Ida K, Lehto Kelli, Gatz Margaret, Reynolds Chandra A, Dahl Aslan Anna K

Abstract excerpt

BACKGROUND: While a high body mass index (BMI) in midlife is associated with higher risk of dementia, high BMI in late-life may be associated with lower risk. This study combined genetic designs with longitudinal data to achieve a better understanding of this paradox. METHODS: We used longitudinal data from 22,156 individuals in the Swedish Twin Registry (STR) and 25,698 from the Health and Retirement Study...

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Identifiers

PMID: 32513281
DOI: 10.1186/s12916-020-01600-2
PMCID: PMC7282125

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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