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From cells to clinic: Single-cell transcriptomics shaping the future of orthopedics

28 May 2025

Abstract excerpt

Single-cell RNA sequencing (scRNA-seq) technology hold significant potential for advancing orthopedic research. This review examines the impact of ScRNA-seq on the future development of orthopedic research and practice. In the study of osteoarthritis, scRNA-seq can finely characterize the changes in the subsets of chondrocytes and their role in disease progression. In rheumatoid arthritis, this technique reveals...

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PMID: 40510239
DOI: 10.1016/j.jot.2025.05.001

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