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Single-cell transcriptomic analysis of chondrocytes in cartilage and pathogenesis of osteoarthritis

2 Feb 2024

Abstract excerpt

Chondrocyte is considered the only cell type in cartilage. However, the cell heterogeneity of chondrocytes in human articular cartilage is still not well defined, which hinders our understanding of the pathogenesis of osteoarthritis (OA). Here, we constructed a single-cell transcriptomic atlas of chondrocytes in healthy cartilage and identified nine chondrocyte subsets including homeostatic chondrocytes,...

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Cancer-related molecular mechanisms research
Chemokine receptors and signaling
Osteoarthritis Treatment and Mechanisms

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39759119
DOI: 10.1016/j.gendis.2024.101241

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