Article
The divergent impact of catechol-O-methyltransferase (COMT) Val158Met genetic polymorphisms on executive function in adolescents with discrete patterns of childhood adversity.
Comprehensive psychiatry - 1 Feb 2018
Zhang Huihui, Li Jie, Yang Bei, Ji Tao, Long Zhouting, Xing Qiquan, Shao Di, Bai Huayu, Sun Jiwei, Cao Fenglin
Abstract excerpt
PURPOSE: Catechol-O-methyltransferase (COMT) Val158Met functional polymorphisms play a crucial role in the development of executive function (EF), but their effect may be moderated by environmental factors such as childhood adversity. The present study aimed at testing the divergent impact of the COMT Val158Met genotype on EF in non-clinical adolescents with discrete patterns of childhood adversity. METHODS: A...
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