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Article

Integrative analysis identifies an immune-relevant epigenetic signature for prognostication of non-G-CIMP glioblastomas.

Oncoimmunology - 29 Mar 2021

Yin Anan, Shang Zhende, Etcheverry Amandine, He Yalong, Aubry Marc, Lu Nan, Liu Yuhe, Mosser Jean, Lin Wei, Zhang Xiang, Dong Yu

Abstract excerpt

The clinical and molecular implications of DNA methylation alterations remain unclear among the majority of glioblastomas (GBMs) without glioma-CpGs island methylator phenotype (G-CIMP); integrative multi-level molecular profiling may provide useful information. Independent cohorts of non-G-CIMP GBMs or IDH wild type (wt) lower-grade gliomas (LGGs) from local and public databases with DNA methylation and gene...

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Identifiers

PMID: 33854822
DOI: 10.1080/2162402X.2021.1902071
PMCID: PMC8018210

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