Article

Novel epigenetic signature of DNA damage response genes for prognostication and immunophenotype of non-G-CIMP glioblastomas

2021-08-23

Abstract excerpt

<title>Abstract</title> <p>Background Dysregulation and dysfunction of DNA damage response (DDR) have prognostic and predictive implications for glioblastomas (GBMs) without glioma-CpGs island methylator phenotype (G-CIMP); mathematical modeling based on DNA methylation abnormality in DDR genes may serve as clinically useful biomarkers. Methods Independent cohorts of non-G-CIMP GBMs and IDH wild type (wt) lower...

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Literature Corpus work: 6a1c26e3-d1dd-585b-9341-f7568b34c602
DOI: 10.21203/rs.3.rs-823543/v1

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