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Article

Molecular and clinicopathological characterization of a prognostic immune gene signature associated with MGMT methylation in glioblastoma

2020-07-17

Abstract excerpt

<h4>Background</h4> O6-methylguanine-DNA methyltransferase (MGMT) methylation status affects tumor chemo-resistance and the prognosis of glioblastoma (GBM) patients. We aimed to investigate the role of MGMT methylation in the regulation of GBM immunophenotype and discover an effective biomarker to improve prognosis prediction of GBM patients. <h4>Methods</h4> A total of 769 GBM patients with clinical information...

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Literature Corpus work
188e6066-82c4-5da6-81fc-d6800f32d3b4
DOI
10.1101/2020.07.16.206318
Open publication

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Molecular and clinicopathological characterization of a prognostic immune gene signature associated with MGMT methylation in glioblastomaDOI 10.1101/2020.07.16.206318
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