Article
A stromal progenitor and ILC2 niche promotes muscle eosinophilia and fibrosis-associated gene expression
1 Apr 2021
Abstract excerpt
Despite the well-accepted view that chronic inflammation contributes to the pathogenesis of Duchenne muscular dystrophy (DMD), the function and regulation of eosinophils remain an unclear facet of type II innate immunity in dystrophic muscle. We report the observation that group 2 innate lymphoid cells (ILC2s) are present in skeletal muscle and are the principal regulators of muscle eosinophils during muscular...
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