Article
An ST2-dependent role of bone marrow-derived group 2 innate lymphoid cells in pulmonary fibrosis.
The Journal of pathology - 1 Aug 2018
Zhao Yuyue, De Los Santos Francina Gonzalez, Wu Zhe, Liu Tianju, Phan Sem H
Abstract excerpt
Recent evidence supports that bone marrow (BM)-derived hematopoietic progenitor cells play an important role in lung injury and fibrosis. While these cells give rise to multiple cell types, the ST2 (Il1rl1)-expressing group 2 innate lymphoid cells (ILC2s) derived from BM progenitors have been implicated in tissue repair and remodeling, including in lung fibrosis. To further investigate the precise role of...
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