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Article

Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 339 adults from Managua, Nicaragua.

Human immunology - 1 Jan 2018

Weiskopf Daniela, Grifoni Alba, Arlehamn Cecilia S Lindestam, Angelo Michael, Leary Shay, Sidney John, Frazier April, Mack Steven J, Phillips Elizabeth, Mallal Simon, Cerpas Cristhiam, Balmaseda Angel, Harris Eva, Sette Alessandro

Abstract excerpt

DNA sequence-based typing at the HLA-A, -B, -C, -DPB1, -DQA1, -DQB1, and -DRB1 loci was performed on anonymized samples provided by 339 healthy adult blood bank donors in Managua, Nicaragua. The purpose of the study was to characterize allele frequencies in the local population to support studies of T cell immunity against pathogens, including Dengue virus. Deviations from Hardy Weinberg proportions were detected...

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Identifiers

PMID: 29122684
DOI: 10.1016/j.humimm.2017.11.002
PMCID: PMC5788571

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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