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Bioreactor production of rVSV‐based vectors in Vero cell suspension cultures

10 Apr 2021

Abstract excerpt

Abstract The Vero cell line is the most used continuous cell line in viral vaccine manufacturing. This adherent cell culture platform requires the use of surfaces to support cell growth, typically roller bottles, or microcarriers. We have recently compared the production of rVSV‐ZEBOV on Vero cells between microcarrier and fixed‐bed bioreactors. However, suspension cultures are considered superior with regard to...

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PMID: 33837958
DOI: 10.1002/bit.27785

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