Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Generation of stable suspension producer cell lines for serum‐free lentivirus production

1 May 2024

Abstract excerpt

Abstract The production of lentiviral vectors (LVs) pseudotyped with the vesicular stomatitis virus envelope glycoprotein (VSV‐G) is limited by the associated cytotoxicity of the envelope and by the production methods used, such as transient transfection of adherent cell lines. In this study, we established stable suspension producer cell lines for scalable and serum‐free LV production derived from two stable,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to RNA Interference and Gene Delivery
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38719592
DOI: 10.1002/biot.202400090

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Generation of stable suspension producer cell lines for serum‐free lentivirus productionPMID 38719592Read ↗

Rapid Lentiviral Vector Producer Cell Line Generation Using a Single DNA ConstructSemantic proximity Read ↗

Development of Lentiviral Packaging Cells and Scale Up of Production to Meet the Growing Demand in Cell and Gene TherapySemantic proximity Read ↗

Inducible Packaging Cells for Large-scale Production of Lentiviral Vectors in Serum-free Suspension CultureSemantic proximity Read ↗

Production of Lentiviral Vectors Using Suspension Cells Grown in Serum-free MediaSemantic proximity Read ↗

Scalable Lentiviral Vector Production Using Stable HEK293SF Producer Cell LinesSemantic proximity Read ↗

Establishment and Characterization of a Stable Producer Cell Line Generation Platform for the Manufacturing of Clinical-Grade Lentiviral VectorsSemantic proximity Read ↗

Production of lentiviral vectorsSemantic proximity Read ↗

Lentiviral vector packaging and producer cell lines yield titers equivalent to the industry-standard four-plasmid processSemantic proximity Read ↗

Generation of a high-titer packaging cell line for the production of retroviral vectors in suspension and serum-free mediaSemantic proximity Read ↗

Development of Third-generation Cocal Envelope Producer Cell Lines for Robust Lentiviral Gene Transfer into Hematopoietic Stem Cells and T-cellsSemantic proximity Read ↗

A New-Generation Stable Inducible Packaging Cell Line for Lentiviral VectorsSemantic proximity Read ↗

Construction of stable packaging cell lines for clinical lentiviral vector productionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.