Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures

29 Jun 2022

Abstract excerpt

Abstract Oncolytic viruses (OVs) represent a novel class of immunotherapeutics under development for the treatment of cancers. OVs that express a cognate or transgenic fusion protein is particularly promising as their enhanced intratumoral spread via syncytia formation can be a potent mechanism for tumor lysis and induction of antitumor immune responses. Rapid and efficient fusion of infected cells results in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to Viral gastroenteritis research and epidemiology
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35767011
DOI: 10.1007/s00253-022-12027-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension culturesPMID 35767011Read ↗

Process intensification strategies toward cell culture‐based high‐yield production of a fusogenic oncolytic virusSemantic proximity Read ↗

Characterization of a quail suspension cell line for production of a fusogenic oncolytic virusSemantic proximity Read ↗

From single‐cell cloning to high‐yield influenza virus production – implementing advanced technologies in vaccine process developmentSemantic proximity Read ↗

Generation of stable suspension producer cell lines for serum‐free lentivirus productionSemantic proximity Read ↗

Production of Oncolytic Measles Virus in Vero Cells: Impact of Culture Medium and Multiplicity of InfectionSemantic proximity Read ↗

Bioreactor production of rVSV‐based vectors in Vero cell suspension culturesSemantic proximity Read ↗

Scalable Recombinant Adeno-Associated Virus Production Using Recombinant Herpes Simplex Virus Type 1 Coinfection of Suspension-Adapted Mammalian CellsSemantic proximity Read ↗

A scalable downstream process for the purification of the cell culture-derived Orf virus for human or veterinary applicationsSemantic proximity Read ↗

Designing cell lines for viral vaccine production: Where do we stand?Semantic proximity Read ↗

Towards a scalable bioprocess for rAAV production using a HeLa stable cell lineSemantic proximity Read ↗

Simian adenovirus vector production for early-phase clinical trials: A simple method applicable to multiple serotypes and using entirely disposable product-contact componentsSemantic proximity Read ↗

Reovirus variants with mutations in genome segments S1 and L2 exhibit enhanced virion infectivity and superior oncolysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.