Article
Lack of association of CD44-rs353630 and CHI3L2-rs684559 with pancreatic ductal adenocarcinoma survival.
Scientific reports - 7 Apr 2021
Gentiluomo Manuel, Corradi Chiara, Vanella Giuseppe, Johansen Astrid Z, Strobel Oliver, Szentesi Andrea, Milanetto Anna Caterina, Hegyi Péter, Kupcinskas Juozas, Tavano Francesca, Neoptolemos John P, Bozzato Dania, Hackert Thilo, Pezzilli Raffaele, Johansen Julia S, Costello Eithne, Mohelnikova-Duchonova Beatrice, van Eijck Casper H J, Talar-Wojnarowska Renata, Hansen Carsten Palnæs, Darvasi Erika, Chen Inna M, Cavestro Giulia Martina, Soucek Pavel, Piredda Liliana, Vodicka Pavel, Gazouli Maria, Arcidiacono Paolo Giorgio, Canzian Federico, Campa Daniele, Capurso Gabriele
Abstract excerpt
Although pancreatic ductal adenocarcinoma (PDAC) survival is poor, there are differences in patients' response to the treatments. Detection of predictive biomarkers explaining these differences is of the utmost importance. In a recent study two genetic markers (CD44-rs353630 and CHI3L2-rs684559) were reported to be associated with survival after PDAC resection. We attempted to replicate the associations in 1856...
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