Article
CD44 SNPrs187115: A Novel Biomarker Signature that Predicts Survival in Resectable Pancreatic Ductal Adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2016
Stracquadanio Giovanni, Vrugt Bart, Flury Renata, Schraml Peter, Würl Peter, Müller Thomas H, Knippschild Uwe, Henne-Bruns Doris, Breitenstein Stefan, Clavien Pierre-Alain, Graf Rolf, Bond Gareth L, Grochola Lukasz F
Abstract excerpt
PURPOSE: Although pancreatic ductal adenocarcinoma (PDAC) is an aggressive tumor, like other common cancers, it displays a wide range of biology. However, at present, there are no reliable tests to predict patients' cancer-specific outcomes and guide personalized treatment decisions. In this study, we aim to identify such biomarkers in resectable PDAC by studying SNPs in the CD44 gene, which drives the...
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