Article
Lack of replication of seven pancreatic cancer susceptibility loci identified in two Asian populations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Feb 2013
Campa Daniele, Rizzato Cosmeri, Bauer Andrea S, Werner Jens, Capurso Gabriele, Costello Eithne, Talar-Wojnarowska Renata, Jamroziak Krzysztof, Pezzilli Raffaele, Gazouli Maria, Khaw Kay-Tee, Key Timothy J, Bambi Franco, Mohelnikova-Duchonova Beatrice, Heller Anette, Landi Stefano, Vodickova Ludmila, Theodoropoulos George, Bugert Peter, Vodicka Pavel, Hoheisel Jörg D, Delle Fave Gianfranco, Neoptolemos John P, Soucek Pavel, Büchler Markus W, Giese Nathalia, Canzian Federico
Abstract excerpt
BACKGROUND: Two recent genome-wide association studies (GWAS) of pancreatic ductal adenocarcinoma (PDAC), conducted, respectively, in a Japanese and in a Chinese population, identified eight novel loci affecting PDAC risk. METHODS: We attempted to replicate the novel loci in a series of PDACs and healthy controls of European ancestry in the context of the newly formed PANcreatic Disease ReseArch (PANDoRA)...
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