Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study.

Leukemia & lymphoma - 1 Apr 2019

Knez Virginia, Liu Xin, Schowinsky Jeffrey, Pan Zenggang, Wang Dehua, Lorsbach Robert, Lu Chuanyi, Luedke Catherine, Haag Mary, Carstens Billie, Swisshelm Karen, Yang Lian-He, Jug Rachel, Wang Endi, Liang Xiayuan

Abstract excerpt

Acute lymphoblastic leukemia (ALL) in infants <1-year-old is biologically different from ALL in older children. Although KMT2A rearrangement is the predominant genetic signature in infantile B-ALL, disease course is heterogenous, behaving more aggressively in younger infants. We investigated clinicopathological differences throughout the first year to understand the transition to pediatric B-ALL. In a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antineoplastic Combined Chemotherapy Protocols
Share to Biopsy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Transformation, Neoplastic

Share to Chromosome Aberrations

Share to Flow Cytometry

Share to Histocytochemistry

Share to Karyotyping

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Source

Identifiers

PMID: 30188223
DOI: 10.1080/10428194.2018.1508667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study.PMID 30188223Read ↗

Updates in the biology and therapy for infant acute lymphoblastic leukemiaSemantic proximity Read ↗

Crossing Our T’s: An Unusual Presentation of Infantile T-cell LeukemiaSemantic proximity Read ↗

Is acute lymphoblastic leukemia with mature B-cell phenotype and KMT2A rearrangements a new entity? A systematic review and meta-analysis.Semantic proximity Read ↗

Updates in KMT2A Gene Rearrangement in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Biology of Childhood Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

KMT2A rearranged acute lymphoblastic leukaemia: Unravelling the genomic complexity and heterogeneity of this high-risk disease.Semantic proximity Read ↗

Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Unraveling the cellular origin and clinical prognostic markers of infant B-cell acute lymphoblastic leukemia using genome-wide analysisSemantic proximity Read ↗

Pediatric therapy-related hematologic neoplasms show enrichment for KMT2A rearrangement and lymphoblastic phenotype.Semantic proximity Read ↗

Minimal residual disease and outcome characteristics in infant KMT2A-germline acute lymphoblastic leukaemia treated on the Interfant-06 protocolSemantic proximity Read ↗

Multiple Lineage Switches in KMT2A Rearranged Infant Leukemia, Responsive to Combination Therapy with CPX-351 and InotuzumabSemantic proximity Read ↗

Towards targeted therapy for infant acute lymphoblastic leukaemia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.