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Article

Mucosal Epithelial Jak Kinases in Health and Diseases.

Mediators of inflammation - 1 Jan 2021

Kumar Narendra, Kuang Longxiang, Villa Ryan, Kumar Priyam, Mishra Jayshree

Abstract excerpt

Janus kinases (Jaks) are a family of nonreceptor tyrosine kinase that include four different members, viz., Jak1, Jak2, Jak3, and Tyk2. Jaks play critical roles in immune cells functions; however, recent studies suggest they also play essential roles in nonimmune cell physiology. This review highlights the significance of epithelial Jaks in understanding the molecular basis of some of the diseases through...

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Identifiers

PMID: 33814980
DOI: 10.1155/2021/6618924
PMCID: PMC7990561

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