Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Janus kinases in immune cell signaling

1 Mar 2009

Abstract excerpt

The Janus family kinases (Jaks), Jak1, Jak2, Jak3, and Tyk2, form one subgroup of the non-receptor protein tyrosine kinases. They are involved in cell growth, survival, development, and differentiation of a variety of cells but are critically important for immune cells and hematopoietic cells. Data from experimental mice and clinical observations have unraveled multiple signaling events mediated by Jaks in innate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to Immune Cell Function and Interaction
Share to Myeloproliferative Neoplasms: Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19290934
DOI: 10.1111/j.1600-065x.2008.00754.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Janus kinases in immune cell signalingPMID 19290934Read ↗

JAKs in pathology: role of Janus kinases in hematopoietic malignancies and immunodeficiencies.Semantic proximity Read ↗

The Janus kinases (Jaks)Semantic proximity Read ↗

Janus Kinase 3 (JAK3): A Critical Conserved Node in Immunity Disrupted in Immune Cell Cancer and ImmunodeficiencySemantic proximity Read ↗

Regulation of T cell homeostasis by JAKs and STATsSemantic proximity Read ↗

Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunitySemantic proximity Read ↗

Janus Kinases in LeukemiaSemantic proximity Read ↗

JAK Kinases in Health and Disease: An UpdateSemantic proximity Read ↗

Malignant JAK-signaling: at the interface of inflammation and malignant transformationSemantic proximity Read ↗

Janus kinase inhibitors: A therapeutic strategy for cancer and autoimmune diseasesSemantic proximity Read ↗

Responses to Cytokines and Interferons that Depend upon JAKs and STATs.Semantic proximity Read ↗

JAKs and STATs in immunity, immunodeficiency, and cancer.Semantic proximity Read ↗

Series Introduction: JAK-STAT signaling in human diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.