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Article

The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.

International journal of molecular sciences - 12 Nov 2021

Kolakowski Damian, Rzepnikowska Weronika, Kaniak-Golik Aneta, Zoladek Teresa, Kaminska Joanna

Abstract excerpt

VPS13 proteins are evolutionarily conserved. Mutations in the four human genes (VPS13A-D) encoding VPS13A-D proteins are linked to developmental or neurodegenerative diseases. The relationship between the specific localization of individual VPS13 proteins, their molecular functions, and the pathology of these diseases is unknown. Here we used a yeast model to establish the determinants of Vps13's interaction with...

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PMID: 34830155
DOI: 10.3390/ijms222212274
PMCID: PMC8619211

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The GTPase Arf1 Is a Determinant of Yeast Vps13 Localization to the Golgi Apparatus.PMID 34830155Read ↗

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