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Article

Construction of Whole Genomes from Scaffolds Using Single Cell Strand-Seq Data.

International journal of molecular sciences - 31 Mar 2021

Hills Mark, Falconer Ester, O'Neill Kieran, Sanders Ashley D, Howe Kerstin, Guryev Victor, Lansdorp Peter M

Abstract excerpt

Accurate reference genome sequences provide the foundation for modern molecular biology and genomics as the interpretation of sequence data to study evolution, gene expression, and epigenetics depends heavily on the quality of the genome assembly used for its alignment. Correctly organising sequenced fragments such as contigs and scaffolds in relation to each other is a critical and often challenging step in the...

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Identifiers

PMID: 33807210
DOI: 10.3390/ijms22073617
PMCID: PMC8037727

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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