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Article

Strand-seq and the future of personalized genomics.

Nature genetics - 1 May 2026

Hanlon Vincent C T, Lansdorp Peter M

Abstract excerpt

Sequencing the human genome came with the promise of refined risk assessment for heritable diseases, drug responses and other applications of personalized genomics. Genome-wide association studies that linked thousands of genetic alterations to heritable disorders have partially delivered on this promise. However, many patients with rare diseases remain undiagnosed after genome sequencing, in part because...

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PMID: 41882415
DOI: 10.1038/s41588-026-02548-4

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