Article
Single-Molecule Sequencing Reveals the Chromosome-Scale Genomic Architecture of the Nematode Model Organism Pristionchus pacificus.
Cell reports - 17 Oct 2017
Rödelsperger Christian, Meyer Jan M, Prabh Neel, Lanz Christa, Bemm Felix, Sommer Ralf J
Abstract excerpt
The nematode Pristionchus pacificus is an established model for integrative evolutionary biology and comparative studies with Caenorhabditis elegans. While an existing genome draft facilitated the identification of several genes controlling various developmental processes, its high degree of fragmentation complicated virtually all genomic analyses. Here, we present a de novo genome assembly from single-molecule,...
Topics
- Animals
- Caenorhabditis elegans
- Chromosomes
- Genetic Linkage
- Genetic Variation
- Genome, Helminth
- Models, Biological
- Nematoda
- Nucleotides
- Phylogeny
- Sequence Analysis, DNA