Article
A Novel Anti-Inflammatory d-Peptide Inhibits Disease Phenotype Progression in an ALS Mouse Model.
Molecules (Basel, Switzerland) - 13 Mar 2021
Post Julia, Kogel Vanessa, Schaffrath Anja, Lohmann Philipp, Shah N Jon, Langen Karl-Josef, Willbold Dieter, Willuweit Antje, Kutzsche Janine
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterised by selective neuronal death in the brain stem and spinal cord. The cause is unknown, but an increasing amount of evidence has firmly certified that neuroinflammation plays a key role in ALS pathogenesis. Neuroinflammation is a pathological hallmark of several neurodegenerative disorders and has been implicated as driver...
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