Genetic Variations Within METTL16 and Susceptibility to Sudden Cardiac Death in Chinese Populations With Coronary Artery Disease.

doi:10.1016/j.amjcard.2023.06.062

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Genetic Variations Within METTL16 and Susceptibility to Sudden Cardiac Death in Chinese Populations With Coronary Artery Disease.

The American journal of cardiology - 1 Sept 2023

Zhen Xiaoyuan, Zhao Wenfeng, Wang Jiawen, Li Lijuan, He Yan, Zhang Jianhua, Li Chengtao, Zhang Suhua, Huang Jiang, Luo Bin, Gao Yuzhen

Abstract excerpt

Despite recent advances in the prevention of coronary heart disease, the mortality rate of sudden cardiac death (SCD) remains high, which has become a substantial public health issue. Methyltransferase-like protein 16 (METTL16), as a newly discovered m6A methyltransferase, may be related to cardiovascular diseases. In the present study, a 6-base-pair insertion/deletion (del) polymorphism (rs58928048) in the...

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PMID: 37423176
DOI: 10.1016/j.amjcard.2023.06.062

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