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Article

Blood DNA methylation pattern is altered in mesial temporal lobe epilepsy.

Scientific reports - 9 Mar 2017

Long Hong-Yu, Feng Li, Kang Jin, Luo Zhao-Hui, Xiao Wen-Biao, Long Li-Li, Yan Xiao-Xin, Zhou Luo, Xiao Bo

Abstract excerpt

Mesial temporal lobe epilepsy (MTLE) is a common epileptic disorder; little is known whether it is associated with peripheral epigenetic changes. Here we compared blood whole genomic DNA methylation pattern in MTLE patients (n = 30) relative to controls (n = 30) with the Human Methylation 450 K BeadChip assay, and explored genes and pathways that were differentially methylated using bioinformatics profiling. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28276448
DOI: 10.1038/srep43810
PMCID: PMC5343463

Genes

CLCA4
CLCN6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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