Article
Empirical Bayes scan statistics for detecting clusters of disease risk variants in genetic studies.
Biometrics - 1 Dec 2015
McCallum Kenneth J, Ionita-Laza Iuliana
Abstract excerpt
Recent developments of high-throughput genomic technologies offer an unprecedented detailed view of the genetic variation in various human populations, and promise to lead to significant progress in understanding the genetic basis of complex diseases. Despite this tremendous advance in data generation, it remains very challenging to analyze and interpret these data due to their sparse and high-dimensional nature....
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