Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characterization of a novel mCH3 conjugated anti-PcrV scFv molecule

30 Mar 2021

Abstract excerpt

Pseudomonas aeruginosa (PA) is a leading cause of nosocomial infections and death in cystic fibrosis patients. The study was conducted to evaluate the physicochemical structure, biological activity and serum stability of a recombinant anti-PcrV single chain variable antibody fragment genetically attached to the mCH3cc domain. The stereochemical properties of scFv-mCH3 (YFL001) and scFv (YFL002) proteins as well...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Genetics and Biotechnology
Share to Bacteriophages and microbial interactions
Share to Monoclonal and Polyclonal Antibodies Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33785781
DOI: 10.1038/s41598-021-86491-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characterization of a novel mCH3 conjugated anti-PcrV scFv moleculePMID 33785781Read ↗

Monoclonal antibodies derived from B cells in subjects with cystic fibrosis reduce <i>Pseudomonas aeruginosa</i> burden in miceSemantic proximity Read ↗

In silico Identification of Novel Therapeutic Targets and Epitopes among the Essential Hypothetical Protein of Pseudomonas aeruginosa: A Novel Approach for Antivirulence TherapySemantic proximity Read ↗

Design of Epitope‐Based Peptide Vaccine against Pseudomonas aeruginosa Fructose Bisphosphate Aldolase Protein Using ImmunoinformaticsSemantic proximity Read ↗

Solubility, Stability, and Avidity of Recombinant Antibody Fragments Expressed in MicroorganismsSemantic proximity Read ↗

Development of innovative multi-epitope mRNA vaccine against Pseudomonas aeruginosa using in silico approachesSemantic proximity Read ↗

Development of nanobodies as theranostic agents against CMY-2-like class C β-lactamasesSemantic proximity Read ↗

Development of a Functional Antibody by Using a Green Fluorescent Protein Frame as the TemplateSemantic proximity Read ↗

Pyoverdine, the Major Siderophore in<i>Pseudomonas aeruginosa</i>, Evades NGAL RecognitionSemantic proximity Read ↗

Isolation of single chain variable fragment (scFv) specific for Cry1C toxin from human single fold scFv librariesSemantic proximity Read ↗

A microbial expression system for high-level production of scFv HIV-neutralizing antibody fragments in Escherichia coliSemantic proximity Read ↗

Structure-based affinity maturation of a chimeric anti-ricin antibody C4C13.Semantic proximity Read ↗

Design of Epitope Based Peptide Vaccine Against Pseudomonas Aeruginosa Fructose Bisphosphate Aldolase Protein using ImmunoinformaticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.