Article
Pyoverdine, the Major Siderophore in<i>Pseudomonas aeruginosa</i>, Evades NGAL Recognition
1 Jan 2012
Abstract excerpt
Pseudomonas aeruginosa is the most common pathogen that persists in the cystic fibrosis lungs. Bacteria such as P. aeruginosa secrete siderophores (iron-chelating molecules) and the host limits bacterial growth by producing neutrophil-gelatinase-associated lipocalin (NGAL) that specifically scavenges bacterial siderophores, therefore preventing bacteria from establishing infection. P. aeruginosa produces a major...
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