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Article

Development of a Functional Antibody by Using a Green Fluorescent Protein Frame as the Template

3 May 2014

Abstract excerpt

Single-chain variable fragment (scFv) antibodies are widely used as diagnostic and therapeutic agents or biosensors for a majority of human disease. However, the limitations of the present scFv antibody in terms of stability, solubility, and affinity are challenging to produce by traditional antibody screening and expression formats. We describe here a feasible strategy for creating the green fluorescent protein...

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Identifiers

PMID: 24795367
DOI: 10.1128/aem.00936-14

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