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Article

Mixed phenotype acute leukemia in a child associated with a NUP98-NSD1 fusion and NRAS p.Gly61Arg mutation.

Cancer reports (Hoboken, N.J.) - 1 Aug 2021

Ganapathi Shireen S, Raikar Sunil S, Yatsenko Svetlana A, Djokic Miroslav, Bukowinski Andrew

Abstract excerpt

BACKGROUND: Mixed phenotype acute leukemia (MPAL) is a rare subset of acute leukemia in the pediatric population associated with genetic alterations seen in both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML). CASE: We describe a patient with MPAL with a NUP98 (nucleoporin 98)-NSD1 gene fusion (nuclear receptor binding SET domain protein1) and NRAS (neuroblastoma RAS viral oncogene homolog...

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Identifiers

PMID: 33784031
DOI: 10.1002/cnr2.1372
PMCID: PMC8388158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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