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Article

Dissection of haplotype-specific drug response phenotypes in multiclonal malaria isolates.

International journal for parasitology. Drugs and drug resistance - 1 Apr 2021

Nkhoma Standwell C, Ahmed Amel O A, Zaman Sharmeen, Porier Danielle, Baker Zachary, Stedman Timothy T

Abstract excerpt

Natural infections of Plasmodium falciparum, the parasite responsible for the deadliest form of human malaria, often comprise multiple parasite lineages (haplotypes). Multiclonal parasite isolates may exhibit variable phenotypes including different drug susceptibility profiles over time due to the presence of multiple haplotypes. To test this hypothesis, three P. falciparum Cambodian isolates IPC_3445 (MRA-1236),...

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Identifiers

PMID: 33780700
DOI: 10.1016/j.ijpddr.2021.03.001
PMCID: PMC8039770

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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