Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.

doi:10.1186/s12936-020-03339-w

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Piperaquine resistant Cambodian Plasmodium falciparum clinical isolates: in vitro genotypic and phenotypic characterization.

Malaria journal - 25 Jul 2020

Boonyalai Nonlawat, Vesely Brian A, Thamnurak Chatchadaporn, Praditpol Chantida, Fagnark Watcharintorn, Kirativanich Kirakarn, Saingam Piyaporn, Chaisatit Chaiyaporn, Lertsethtakarn Paphavee, Gosi Panita, Kuntawunginn Worachet, Vanachayangkul Pattaraporn, Spring Michele D, Fukuda Mark M, Lon Chanthap, Smith Philip L, Waters Norman C, Saunders David L, Wojnarski Mariusz

Abstract excerpt

BACKGROUND: High rates of dihydroartemisinin-piperaquine (DHA-PPQ) treatment failures have been documented for uncomplicated Plasmodium falciparum in Cambodia. The genetic markers plasmepsin 2 (pfpm2), exonuclease (pfexo) and chloroquine resistance transporter (pfcrt) genes are associated with PP...

Topics

Antimalarials
Cambodia
Drug Resistance
Genetic Markers
Genotype
Phenotype
Plasmodium falciparum
Quinolines

Source

Open in PubMed

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open full text

Identifiers

PMID: 32711538
DOI: 10.1186/s12936-020-03339-w
PMCID: PMC7382038

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-32711538-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.